Funding Resources 2019-07-16T12:31:40+00:00

Funding Resources Available


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Methods to Improve Reproducibility of Human iPSC Derivation, Growth and Differentiation (SBIR) (R44 – Clinical Trial Not Allowed) Human induced pluripotent stem cells (iPSCs) have been used with great success to mimic the differentiation of a variety of tissues, understand early development and study human diseases. Despite approaches that have made the derivation, growth and differentiation of iPSCs more efficient, there remains significant variability in reprogramming efficacy, genomic integrity and developmental potential of iPSCs derived from a single fibroblast or tissue sample. Thus, iPSCs derived from the same sample may differ in their in vitro growth characteristics and their ability to re-differentiate into the desired tissue type. A variety of issues may affect derivation of the iPSCs and their growth, stability and differentiation, including the specific characteristics of the starting cell or tissue sample (e.g., age of donor, tissue type and anatomical location, physiological and disease state), the methods and protocols used to induce pluripotency (e.g., transcription factors, small molecules, cell fusion), the choice of growth factors and other culture conditions, method of storage of cell lines, etc. Further challenges include growing and maintaining sufficient quantities of iPSC lines in culture without changes in their properties, as well as the ability of multiple investigators to identify and authenticate iPSC lines as part of their research. This Funding Opportunity Announcement (FOA) will support SBIR projects to develop novel, reliable and cost-effective methods to standardize and increase the utility and reproducibility of iPSCs at all stages, from their derivation to their research and clinical applications. https://grants.nih.gov/grants/guide/rfa-files/RFA-GM-19-001.html 12-06-19 01-06-20
Sartorius & Science Prize for Regenerative Medicine & Cell Therapy The Sartorius & Science Prize for Regenerative Medicine & Cell Therapy is an annual prize geared toward researchers focused on basic or translational research that advances regenerative medicine and cell therapy; for example cell-, gene-, or immunotherapy, tissue engineering, and materials engineering. Established in 2017, the prize is awarded for outstanding research performed by the applicant and as described in a 1,000 word essay.
The winner of the Sartorius & Science Prize for Regenerative Medicine & Cell Therapy is awarded US$25,000 and publication of his or her essay in Science. The Grand Prize essay and that of the Runner-up are also published on Science Online. The award is announced and presented at a ceremony for which Sartorius will provide financial support to help enable the grand prize winner to attend the ceremony
https://www.sciencemag.org/prizes/sartorius-science-prize-regenerative-medicine-cell-therapy Now 10-01-19
PAR-18-547: UG3/UH3 NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) https://grants.nih.gov/grants/guide/pa-files/par-18-547.html 01-23-18 01-08-21
PAR-18-530: R01 Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 – Clinical Trial Optional) https://grants.nih.gov/grants/guide/pa-files/PAR-18-530.html 02-28-18 01-08-21
PAR-16-093: R01 Improvement of Animal Models for Stem Cell-Based Regenerative Medicine (R01) https://grants.nih.gov/grants/guide/pa-files/PAR-16-093.html 05-05-16 05-08-19
PAR-16-094: R21 Improvement of Animal Models for Stem Cell-Based Regenerative Medicine (R21) https://grants.nih.gov/grants/guide/pa-files/PAR-16-094.html 03-08-16 05-08-19
PA-18-574: R43, R44 PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) https://grants.nih.gov/grants/guide/pa-files/PA-18-574.html 03-05-18 04-06-19
PA 18-575: R41, R42 PHS 2018-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) https://grants.nih.gov/grants/guide/pa-files/PA-18-575.html 03-05-18 04-06-19
NOT-EB-18-026: R01 Notice of Intent to Issue the Funding Opportunity Announcement for Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed) https://grants.nih.gov/grants/guide/notice-files/NOT-EB-18-026.html 02-19-18 TBD
PA-19-075, R41 /R42 Enabling Technologies to Accelerate Development of Oral Biodevices (R41/R42 Clinical Trial Not Allowed) https://grants.nih.gov/grants/guide/pa-files/PA-19-075.html 03-05-19 01-06-2022
PA-19-076, R43/R44 Enabling Technologies to Accelerate Development of Oral Biodevices (R43/R44 Clinical Trial Not Allowed) https://grants.nih.gov/grants/guide/pa-files/PA-19-076.html 03-05-19 01-06-2022

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