Principal Investigators 2019-01-11T14:41:19+00:00


David H. Kohn, PhD

Dr. Kohn is a Professor at the University of Michigan in the Departments of Biologic and Materials Sciences (Dentistry) and Biomedical Engineering (Engineering). He received his BS in biomedical engineering from Tulane University and his Ph.D. in bioengineering from the University of Pennsylvania. Dr. Kohn’s laboratory focuses on biomineralization, which is investigated by establishing structure-function relations in mineralized tissues and utilizing this information to develop biomimetic strategies to engineer tissue. Over the past 30 years, Dr. Kohn’s research has spanned numerous areas, including biomineralization, biomimetic materials, discovery of novel dual-function peptides, and functional adaptation of tissues in response to exercise, diet and genetic influences. Dr. Kohn is also the PI and Director of Michigan’s NIH-supported Training Program in Tissue Engineering and Regeneration and is President of the Society for Biomaterials. Dr. Kohn serves on the advisory boards of several universities and has consulted for many medical device companies. Dr. Kohn is a Fellow of Biomaterials Science and Engineering of the International Union of Societies for Biomaterials Science, and a Fellow of the American Institute of Medical and Biological Engineering (AIMBE) and American Association for the Advancement of Science (AAAS). He is also a recipient of a Distinguished Scientist award from the International Association for Dental Research (IADR).

William V. Giannobile, DDS, DMSc

Dr. William Giannobile is the Najjar Endowed Professor & Chair of the Department of Periodontics and Oral Medicine at the University of Michigan School of Dentistry. He is also a Professor of Biomedical Engineering at the College of Engineering. He received his DDS and MS in Oral Biology from the University of Missouri. He later received his Certificate in Periodontology and Doctor of Medical Sciences in Oral Biology from Harvard University. He completed postdoctoral training in Molecular Biology at the Dana-Farber Cancer Institute and Harvard Medical School. Dr. Giannobile previously served as a faculty member at Harvard and the Forsyth Institute. He has served as a Visiting Professor at the University of Genoa Medical School Biotechnology Institute and in the Department of Periodontology at the Eastman Dental Institute, University College London.

Dr. Giannobile’s continuously funded research program over the past 20 years has focused on Oral and Periodontal Regenerative Medicine, Tissue Engineering and Personalized Medicine. Dr. Giannobile currently serves as the Editor-in-Chief for the Journal of Dental Research, the official journal of the International Association for Dental Research. He is a past-president of the American Academy of Periodontology Foundation. Dr. Giannobile is a consultant to the U.S. Food and Drug Administration for Dental Devices. Dr. Giannobile has received numerous awards including the Jan Lindhe International Periodontal Award, the Distinguished Scientist Award and William J. Gies Award from the American Academy of Periodontology for his research contributions. He is a diplomate of the American Board of Periodontology and practices Periodontology and Implant Dentistry in Ann Arbor, Michigan.

David Mooney, PhD

Dr. Mooney is the Pinkas Family Professor of Bioengineering at Harvard University and Core Faculty Member at the Wyss Institute. He is a member of the National Academy of Engineering and the National Academy of Medicine. His inventions have been licensed by twelve companies, leading to commercialized products, and he is active on industrial scientific advisory boards.

His laboratory designs biomaterials to make cell and protein therapies effective and practical approaches to treat disease. He is a member of the National Academy of Engineering, the National Academy of Medicine, and the National Academy of Inventors. He has won numerous awards, including the Clemson Award from the SFB, MERIT award from the NIH, Distinguished Scientist Award from the IADR, Phi Beta Kappa Prize for Excellence in Undergraduate Teaching, and the Everett Mendelsohn Excellence in Mentoring Award from Harvard College.

Charles Sfeir, DDS, PhD

Dr. Sfeir is the Associate Dean for Research and the Director of the Center for Craniofacial Regeneration at the University of Pittsburgh. He is also Associate Professor in the Departments of Oral Biology and Periodontics. Dr. Sfeir holds a DDS and a Ph.D. in molecular biology. His research is multidisciplinary and translational in nature, focusing on designing therapies for craniofacial and dental diseases. As a clinician scientist with 3 technologies from his laboratory well underway in the translational pathway, Dr. Sfeir’s expertise in device development as well as in clinical dentistry and craniofacial tissue engineering are invaluable to this resource center.

William R. Wagner, PhD

Dr. Wagner is the Director of the McGowan Institute for Regenerative Medicine as well as a Professor of Surgery, Bioengineering and Chemical Engineering at the University of Pittsburgh. He also serves as Scientific Director of the NSF Engineering Research Center on “Revolutionizing Metallic Biomaterials” and Chief Science Officer for the Armed Forces Institute of Regenerative Medicine.

Professor Wagner is the Founding Editor and Editor-in-Chief of one of the leading biomaterials journals, Acta Biomaterialia, and is a past-president of the American Society for Artificial Internal Organs (ASAIO). Currently he serves as Chairman for the Tissue Engineering and Regenerative Medicine International Society (TERMIS) Americas region. He is a fellow and former vice president of the American Institute for Medical and Biological Engineering (AIMBE) and has also been elected a fellow of the Biomedical Engineering Society, the International Union of Societies for Biomaterials Science and Engineering, TERMIS, and the American Heart Association

Dr. Wagner’s research focuses on areas tissue engineering with projects that address medical device biocompatibility and design, biomaterial development, tissue engineering, and targeted imaging.